hrp0095p1-434 | Diabetes and Insulin | ESPE2022

Role of glucose variability on linear growth in children with Type 1 Diabetes

Castorani Valeria , Blasetti Annalisa , Polidori Nella , Mastromauro Concetta , Mascioli Ilaria , Chiarelli Francesco , Giannini Cosimo

Objective: Linear growth is impaired in children with type 1 diabetes (T1D) and poor metabolic control. A good metabolic control is a key therapeutic goal to prevent vascular complications but also for ensuring an appropriate anthropometric development during childhood. In this study, we aimed to identify and characterize the effects of glycemic variability on linear growth in children with T1D.Methods: Data from 144 pre...

hrp0092p3-274 | Late Breaking Abstracts | ESPE2019

Role of Adiposity Indexes in the Risk of Ketoacidosis (DKA) in Children with Type 1 Diabetes (T1D) at Onset

Castorani Valeria , Pasquarelli Serena , Chiarelli Francesco , Blasetti Annalisa , Mohn Angelika , Giannini Cosimo

Background: DKA is the most serious life-threatening acute complication of T1D. Few data are available evaluating the possible role of anthropadiposity indexes in paediatric DKA in a selected population of prepubertal children. We aimed to identify the possible correlation between adiposity indexes and the presence and severity of DKA at T1D onset.Methods: 195 prepubertal children (84Female/111Male) diagnosed be...

hrp0092p3-314 | Late Breaking Abstracts | ESPE2019

Case Report: Hyperglicemic Iperosmolar State in a Obese Prepubertal Girl with Newly Diagnosis of Type 2 Diabetes

Polidori Nella , Giannini Cosimo , Comegna Laura , Chiarelli Francesco , Blasetti Annalisa , Mohn Angelika

A 11years-old Italian severely obese prepubertal female (BMI: 32.4 kg/m2; SDS-BMI: 2.63) was admitted to the emergency department due to worsening dyspnea and chest pain associated with severe polyuria, lethargy and lost weight from (85 kg to 78 kg in 7 days). She has history of severe hypertension treated with amlodipine and bisoprololo and a positive family history of Type 2 diabetes. At admission, she was dehydrated and lethargic, but can be awakened after painful and verba...